Dementia of the Alzheimer's Type

The development of multiple cognitive deficits manifested by both:
1. memory impairment (impaired ability to learn new information or to recall previously learned information)
2. one (or more) of the following cognitive disturbances:

  • aphasia (language disturbance)
  • apraxia (impaired ability to carry out motor activities despite intact motor function)
  • agnosia (failure to recognize or identify objects despite intact sensory function)
  • disturbance in executive functioning (i.e., planning, organizing, sequencing, abstracting)
  • The cognitive deficits above each cause significant impairment in social or occupational functioning and represent a significant decline from a previous level of functioning. The course is characterized by gradual onset and continuing cognitive decline. The deficits do not occur exclusively during the course of a delirium. The cognitive deficits above are not due to any of the following:

  • other central nervous system conditions that cause progressive deficits in memory and cognition (e.g., cerebrovascular disease, Parkinson's disease, Huntington's disease, subdural hematoma, normal-pressure hydrocephalus, brain tumor)
  • systemic conditions that are known to cause dementia (e.g., hypothyroidism, vitamin B-12 or folic acid deficiency, niacin deficiency, hypercalcemia, neurosyphilis, HIV infection)
  • substance-induced conditions
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